Avilamycin Premix is a well - known feed additive that has gained significant popularity in the livestock and poultry industry. As a reliable supplier of Avilamycin Premix, I am here to delve deep into its composition and explain how it benefits animal husbandry.
1. Core Component: Avilamycin
At the heart of Avilamycin Premix is the active ingredient, avilamycin. Avilamycin is a type of oligosaccharide antibiotic that belongs to the orthosomycin class. It is produced by the fermentation of Streptomyces viridochromogenes.
The chemical structure of avilamycin is quite complex. It consists of a polycyclic core with multiple sugar moieties attached. This unique structure endows avilamycin with its specific antibacterial properties. Avilamycin works by binding to the 50S ribosomal subunit of bacteria, thereby inhibiting bacterial protein synthesis. This mechanism is effective against a wide range of gram - positive bacteria, including some important pathogens in animal production such as Clostridium perfringens, which can cause necrotic enteritis in poultry, and Streptococcus suis, a significant pathogen in swine.
2. Carrier Substances
In addition to the active ingredient, Avilamycin Premix contains carrier substances. These carriers play a crucial role in ensuring the stability, uniformity, and easy handling of the premix.
2.1 Diluents
Common diluents used in Avilamycin Premix include calcium carbonate, corn starch, and rice hulls. Calcium carbonate is a widely used diluent due to its low cost, high purity, and good physical properties. It can effectively dilute the active ingredient to the appropriate concentration and provide a stable matrix for the premix. Corn starch is another popular choice. It is a natural and biodegradable substance that can improve the flowability of the premix and prevent agglomeration. Rice hulls are often used for their good absorbency and low density, which helps in achieving a homogeneous mixture.
2.2 Binders
Binders are added to hold the components of the premix together. Substances like gum arabic and gelatin are sometimes used as binders. Gum arabic is a natural polysaccharide that can form a sticky film around the particles, preventing them from separating during storage and transportation. Gelatin, a protein - based binder, can also enhance the cohesion of the premix and improve its overall physical stability.
3. Comparison with Other Premixes
When considering feed additives, it's essential to compare Avilamycin Premix with other similar products on the market, such as Lincomycin Premix and Enramycin Premix.
Lincomycin Premix contains lincomycin, which is a lincosamide antibiotic. Lincomycin primarily targets gram - positive bacteria and some anaerobic bacteria. However, its mechanism of action is different from that of avilamycin. Lincomycin inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit at a different site compared to avilamycin. This difference in binding site may result in different antibacterial spectra and efficacy.
Enramycin Premix, on the other hand, contains enramycin, a cyclic peptide antibiotic. Enramycin is also effective against gram - positive bacteria, especially those in the gastrointestinal tract of animals. It works by interfering with the synthesis of the bacterial cell wall. Compared to Avilamycin Premix, enramycin has a different mode of action and may offer different benefits in terms of promoting animal growth and preventing diseases.
4. Quality Control and Safety
As a supplier of Avilamycin Premix, we place great emphasis on quality control and safety.
4.1 Quality Control
We have a strict quality control system in place from the raw material sourcing to the final product packaging. For the active ingredient, avilamycin, we ensure that it is produced under Good Manufacturing Practice (GMP) conditions. The purity and potency of avilamycin are regularly tested using high - performance liquid chromatography (HPLC) and other advanced analytical techniques.
For the carrier substances, we source them from reliable suppliers and conduct quality inspections to ensure that they meet our standards. The moisture content, particle size, and chemical composition of the carriers are carefully monitored to ensure the stability and uniformity of the premix.
4.2 Safety
Avilamycin Premix has been approved for use in animal feed in many countries. However, we still follow strict safety guidelines. We provide clear instructions on the proper use of the premix, including the recommended dosage, withdrawal period, and storage conditions. We also conduct regular safety assessments to ensure that the product does not pose any significant risks to animals, humans, or the environment.
5. Benefits of Avilamycin Premix in Animal Husbandry
The unique composition of Avilamycin Premix brings several benefits to animal husbandry.
5.1 Growth Promotion
By controlling the growth of harmful bacteria in the animal's gastrointestinal tract, Avilamycin Premix can improve the nutrient utilization efficiency of animals. This leads to better feed conversion ratios and faster growth rates. In poultry, for example, it can help chicks reach market weight more quickly, reducing the production cycle and increasing profitability.
5.2 Disease Prevention
As mentioned earlier, avilamycin is effective against many gram - positive pathogens. By adding Avilamycin Premix to animal feed, the incidence of diseases such as necrotic enteritis in poultry and diarrhea in swine can be significantly reduced. This not only improves animal health but also reduces the need for therapeutic antibiotics, which is in line with the trend of reducing antibiotic use in animal production.
6. Contact for Purchase and Cooperation
If you are interested in our Avilamycin Premix or have any questions about its composition, usage, or quality, we welcome you to contact us for further discussion. Our team of experts is ready to provide you with detailed information and support to meet your specific needs in animal feed production. Whether you are a large - scale livestock producer or a feed manufacturer, we can offer you high - quality Avilamycin Premix at a competitive price.
References
- "Antibiotics in Animal Nutrition: Use, Misuse, and Alternatives" by John P. Canty.
- "Feed Additives: Principles and Practice" edited by H. M. Edwards and R. O. Baker.
- Research papers on the antibacterial mechanism of avilamycin published in peer - reviewed journals such as Journal of Antibiotics.